Endocytosis-Associated Guanine Nucleotide Exchange Factor Rabgef1 Facilitates the Biogenesis of Outer Segments in Mammalian Photoreceptors
<p> Rod and cone photoreceptors in the retina are polarized sensory neurons that possess uniquely modified primary cilium, called the outer segment, to capture photons. Circadian-mediated shedding and renewal of outer segment membrane discs requires extensive vesicular transport of protein car...
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| Language: | EN |
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The George Washington University
2018
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| Online Access: | http://pqdtopen.proquest.com/#viewpdf?dispub=10690275 |