A fret investigation into molecular mechanisms of cardiac troponin activation in reconstituted thin filaments
<p> Cardiomyopathies (CM) are the leading cause of death in America, and can develop from mutations in sarcomeric proteins, leading to altered protein structure and function. Current therapies target upstream signaling pathways to treat the symptoms of heart failure, but are associated with in...
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| Language: | EN |
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South Dakota State University
2016
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| Online Access: | http://pqdtopen.proquest.com/#viewpdf?dispub=10109377 |