Application of crispr/cas9-based reverse genetics in leishmania braziliensis: Conserved roles for hsp100 and hsp23

Application of crispr/cas9-based reverse genetics in leishmania braziliensis: Conserved roles for hsp100 and hsp23

The protozoan parasite Leishmania (Viannia) braziliensis (L. braziliensis) is the main cause of human tegumentary leishmaniasis in the New World, a disease affecting the skin and/or mucosal tissues. Despite its importance, the study of the unique biology of L. braziliensis through reverse genetics a...

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Bibliographic Details
Main Authors: Adaui, Vanessa, Kröber-Boncardo, Constanze, Brinker, Christine, Zirpel, Henner, Sellau, Julie, Arévalo, Jorge, Dujardin, Jean Claude, Clos, Joachim
Format: Article
Language:English
Published: MDPI AG 2021
Subjects:
CRISPR–Cas9
Gene targeting
Heat shock proteins
Leishmania braziliensis
Phenotyping
Reverse genetics
Animal cell
Article
Controlled study
CRISPR-CAS9 system
Online Access:http://hdl.handle.net/10757/655510

Internet

http://hdl.handle.net/10757/655510

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