Characterization of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced modification of hepatic pyruvate carboxylase gene expression in C57BL/6J male mice

Characterization of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced modification of hepatic pyruvate carboxylase gene expression in C57BL/6J male mice

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure on hepatic pyruvate carboxylase (PC) gene expression were investigated in C57BL/6J Ah[superscipt b/b male mice. A dose-dependent reduction of PC levels and activity occurred in animals given a single intraperitoneal dose of TCDD in a...

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Bibliographic Details
Main Author: Sparrow, Barney R.
Other Authors: Schaup, Henry W.
Language:en_US
Published: 2012
Subjects:
Tetrachlorodibenzodioxin
Pyruvate carboxylase
Mice > Genetics
Genetic toxicology
Online Access:http://hdl.handle.net/1957/34437

Internet

http://hdl.handle.net/1957/34437

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