Development and characterization of a model of glutamate and domoate toxicity in cultured rat cerebellar granule neurons
A model of acute glutamate- and domoate-induced toxicity was developed and characterized in cultured rat cerebellar granule cells (CGCs) using experimental conditions which preserve the voltage-dependency of NMDA receptor function. Glutamate, which is normally non-toxic to CGCs in physiologic media...
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| Language: | en_US |
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2012
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| Online Access: | http://hdl.handle.net/1957/33853 |