Alteration of cholesterol disposition by chlordecone is not explained by induction of cyp7a or cyp4a1
Liver X receptor (LXR), farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR) are adopted orphan nuclear receptors that function as lipid sensors. These receptors respond to cellular lipid levels and regulate the expression of target gene. Previously, it was demonstrated t...
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| Language: | en_US |
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2012
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| Online Access: | http://hdl.handle.net/1957/32450 |