Modulation of deoxyribonucleoside triphosphate levels, DNA synthesis rates and fidelity in mammalian cells
Deoxyribonucleoside triphosphate (dNTP) concentrations measured in cells are not symmetric. dGTP almost always represents only 5-10% of the total dNTP pools in cells. In an in vitro replication system involving semiconservative replication from an SV 40 origin, the mutation frequency of an M13 phage...
Main Author: | Martomo, Stella A. |
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Other Authors: | Mathews, Christopher K. |
Language: | en_US |
Published: |
2012
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Subjects: | |
Online Access: | http://hdl.handle.net/1957/32420 |
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