Modulation of deoxyribonucleoside triphosphate levels, DNA synthesis rates and fidelity in mammalian cells

Deoxyribonucleoside triphosphate (dNTP) concentrations measured in cells are not symmetric. dGTP almost always represents only 5-10% of the total dNTP pools in cells. In an in vitro replication system involving semiconservative replication from an SV 40 origin, the mutation frequency of an M13 phage...

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Bibliographic Details
Main Author: Martomo, Stella A.
Other Authors: Mathews, Christopher K.
Language:en_US
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1957/32420