Regulation of skeletal muscle protein degradation by u-calpain and development of a skeletal muscle-specific inducible expression system
The first goal of this study was to understand the role of u-calpain in skeletal muscle protein degradation in cultured muscle cells. Several strategies were developed to down-regulate endogenous u-calpain activity and m-calpain activity in rat myotubes. These included over-expression of antisense u...
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| Language: | en_US |
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2012
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| Online Access: | http://hdl.handle.net/1957/32264 |