Acute exposure to ethionamide in an Fmo 1/2/4 null murine model
The use of ethionamide has been increasing in drug regiments due to greater incidence of multidrug resistance tuberculosis around the world. Ethionamide is metabolized into antimicrobial relevant compounds by different flavin-containing monooxygenase (FMO) enzymes including FMO1, FMO2, and FMO3. FMO...
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| Language: | en_US |
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2012
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| Online Access: | http://hdl.handle.net/1957/28607 |