A study of the genotoxicity of tyrosine metabolites in rat primary hepatocytes / H.M. Bhabha

Toxicity of tyrosine metabolite has been hypothesiszed, but not proven, to play a role in the ethiopathogenesis of hepatic alterations found in hereditary tyrosinemia type1 (HT1), a metabolic disease caused by a deficiency of fumarylacetoacetate hydrolase (FAH). A deficiency of this enzyme results...

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Bibliographic Details
Main Author: Bhabha, Helen Mafihlase
Published: North-West University 2010
Online Access:http://hdl.handle.net/10394/3637