The pharmacokinetic interaction between cyclosporine and methoxsalen / Máralien Bouwer
Cyclosporine forms the cornerstone of therapy to prevent rejection after organ transplantation. However, the clinical use of the drug is compromised by a narrow therapeutic window and a wide inter- and intra-individual variation in metabolism. Cyclosporine is metabolised by the CYP3A4 isoenzymes in...
| Main Author: | |
|---|---|
| Published: |
North-West University
2009
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10394/331 |