Molecular analysis of the mitochondrial genome in South African patients with suspected mitochondrial disorders / by Anna Catharina van Brummelen
Human mitochondrial DNA (mtDNA) contains 37 genes, which encode 13 proteins (all subunits of the respiratory chain), 22 transfer ribonucleic acids (tRNA), and two ribosomal RNAs. The mtDNA mutation rate is approximately 10 times higher than that of nuclear DNA and mutations therefore accumulate more...
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North-West University
2009
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| Online Access: | http://hdl.handle.net/10394/291 |