Biophysical analysis of the interaction between novel inhibitors and N-acyl ethanolamine acid amidase (NAAA)
N-acylethanolamine acid amidase (NAAA) is an N-terminal nucleophile (NtN) enzyme with a catalytic cysteine residue. The most prominent substrate hydrolyzed is palmitoylethanolamine (PEA), which regulates inflammation. Our inhibitors of NAAA result in increased endogenous leve...
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| Online Access: | http://hdl.handle.net/2047/D20384358 |