Overcoming the blood brain barrier: in vivo and in vitro perfusion model for delivery of Avidin.

The blood-brain barrier (BBB), consists of brain microvascular endothelial cells, pericytes and astrocytes, is a major obstacle that needs to be overcome for drug delivery systems in the brain. Adsorptive-mediated transcytosis (AMT) is one of seven different ways in which drugs or molecules can be t...

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Online Access:http://hdl.handle.net/2047/D20382871