Synthesis of 3-trifluoromethyl-3-pyrimidinyl diazirines as photoreactive amino acid analogs

Photoaffinity labeling is a biochemical technique used for determining binding behavior of biomolecules. A labeled ligand and a target of interest are covalently crosslinked in response to a specific wavelength of light. These irreversibly bound complexes can then be analyzed by Western blot, mass s...

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Online Access:http://hdl.handle.net/2047/D20317956