De novo synthesis of RSK inhibitor analogues: carbasugar kaempferol glycosides; synthesis of epoxydine A and its analogues.
Abstract of Dissertation The p90 ribosomal S6 kinase (RSK) is a family of serine kinase that have been shown to be potential targets for anticancer therapy. Of the four known RSK isoforms, RSK1 and RSK2 are most closely linked to cancer cell growth. In a natural product extract screening effort aime...
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| Online Access: | http://hdl.handle.net/2047/D20316341 |