Top-down proteomic analysis of protein pharmaceuticals, mixtures of protein complexes, and ribosomal protein extracts by capillary zone electrophoresis-mass spectrometry

Mass spectrometry has emerged as a high accuracy, high sensitivity approach for the analysis of proteins. A conventional scheme for protein analysis by mass spectrometry involves reduction, alkylation, proteolytic digestion, followed by analysis either by electrospray ionization mass spectrometry (...

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Online Access:http://hdl.handle.net/2047/D20259955