Conformational analysis of breast tumor kinase SH2 domain by hydrogen exchange mass spectrometry
Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase (NRPTK) that is overexpressed in 2/3 of breast tumors. Brk belongs to a small and highly uncharacterized family of NRPTKs, the Frk family. Despite its segregation on the NRPTK family tree based on genetic and sequential criteria, ma...
| Published: |
|
|---|---|
| Online Access: | http://hdl.handle.net/2047/d20000717 |