Hydrogen/deuterium exchange mass spectrometry reveals the details of intramolecular interactions that affect abelson tyrosine kinase activity
The Abelson protein-tyrosine kinase (c-Abl) is a non-receptor tyrosine kinase ubiquitously expressed in human tissues. c-Abl plays a critical role in many cellular functions including regulation of cell growth, survival, and differentiation, oxidative stress and DNA-damage responses, actin dynamics,...
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| Online Access: | http://hdl.handle.net/2047/d10016351 |