Local hydrogen deuterium exchange mass spectrometry: from pressurized online digestion to pepsin proteolysis.
Higher-order structure of a protein is important for proper biological function. Current analytical and structural methods provide comprehensive understanding of the chemical, physical, and biological characteristics of biologics, yet detecting a change in dynamics and conformation can be a challeng...
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| Online Access: | http://hdl.handle.net/2047/d20003044 |