umuD gene products are molecular adaptors in the regulation of DNA damage tolerance

The homodimeric umuD gene products play key roles in regulating the cellular response to DNA damage in Escherichia coli. UmuD is composed of 139-amino acid subunits and is upregulated as part of the SOS DNA damage response. Subsequently, damage-induced RecA:ssDNA nucleoprotein filaments mediate the...

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Online Access:http://hdl.handle.net/2047/d20002405