Synthesis & evaluation of bipolar biphenyl proteomimetics as nuclear receptor CBIs and applications of palladium chemistry to the development of radiotracers
Protein-protein interactions (PPIs) are essential activation and communication mechanisms for countless biological processes. The ability to inhibit PPIs therefore exposes therapeutic pathways for ailments that may have otherwise been deemed untreatable. Recognition that a subset of PPIs are frequen...
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| Online Access: | http://hdl.handle.net/2047/d20001221 |