Discovery and characterization of lung cancer biomarkers using monoclonal antibody proteomics and liquid chromatography: mass spectrometry of glycopeptides.
Current proteomics strategies for biomarker efforts have two limitations: the neglect of protein glycosylation in discovery/qualification and the lack of antibodies for verification/validation. The main goal of this thesis is to address these two problems. For the lack of high quality antibodies, mo...
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| Online Access: | http://hdl.handle.net/2047/d20000801 |