Exploring the early effects of AP endonuclease 1 knockdown in zebrafish embryogenesis
AP Endonuclease 1 (Apex1) is a major player in the base excision repair (BER) pathway, which accounts for the majority of oxidative DNA damage repair in eukaryotic cells. Loss of Apex1 in developing vertebrate embryos, whether by artificial knockdown or genetic knockout, is lethal and halts developm...
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| Online Access: | http://hdl.handle.net/2047/d20002985 |