Characterization and eradication of persisters in Candida albicans biofilms

Fungal pathogens form biofilms that are highly recalcitrant to antimicrobial therapy. We report that biofilms formed by the major human pathogen Candida albicans exhibit biphasic killing in response to amphotericin B and chlorhexidine. Biphasic killing indicates the existence of a subpopulation of h...

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Online Access:http://hdl.handle.net/2047/d10016247