Role of type O-glycosylation in the cytotoxic activity of various chemotherapeutic agents as a function of their physicochemical properties: evaluation of mucinous cancer cell lines.
Mucins are cell surface glycoproteins with protective functions. They are over-expressed in a variety of cancerous conditions. In addition to protection, lubrication and signal transduction functions they have long been implicated in the invasion, metastasis, poor prognosis and extremely poor surviv...
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| Online Access: | http://hdl.handle.net/2047/d10017112 |