In vitro evaluations of multifunctional nanoparticles for simultaneous EGFR gene silencing and drug delivery in pancreatic cancer

Pancreatic cancer, a lethal malignancy is difficult to diagnose and is associated with poor prognosis due to distal dissemination of the cancer to organs such as the liver, spleen and gastrointestinal tract. Epidermal growth factor receptor (EGFR), a member of ErbB family of growth factor receptors,...

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Online Access:http://hdl.handle.net/2047/d10018736