Reversal of the multidrug resistance by drug combination using multifunctional liposomes
One of the major obstacles to the success of cancer chemotherapy is the multi-drug resistance (MDR) that results due mainly to the over-expression of drug efflux transporter pumps such as P-glycoprotein (P-gp). Highly efficacious third generation P-gp inhibitors, like tariquidar, have shown promisin...
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| Online Access: | http://hdl.handle.net/2047/d20003274 |