Novel neurotrophic growth factor signaling pathway mediates changes in epigenetics through the redox and methylation influence of EAAT3-mediated cysteine uptake
The level of oxidative stress increases with age, and abnormal elevations are a hallmark of many neurological and neuropsychiatric disorders, including Alzheimer's disease. In neurons, the glutamate, aspartate, and cysteine transporter EAAT3 is the predominant transporter of cysteine, the rate-...
| Published: |
|
|---|---|
| Online Access: | http://hdl.handle.net/2047/d20002977 |