Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance
The immune system is highly organized and multifunctional; it protects the organism against invading pathogens (immune response), while at the same time being tolerant to ‘self’ (immune tolerance). Central tolerance is achieved during T-cell development by negative selection via self-peptide-MHC com...
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Ludwig-Maximilians-Universität München
2014
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| Online Access: | http://edoc.ub.uni-muenchen.de/16514/1/Wu_Chunyan.pdf http://nbn-resolving.de/urn:nbn:de:bvb:19-165140 |