Defective DNA repair in EGFR-mutant lung cancer

In patients with lung cancer whose tumors harbor activating mutations in the EGF receptor (EGFR), increased responses to platinum-based chemotherapies are seen compared with wild-type cancers. However, the mechanisms underlying this association have remained elusive. Here, we describe a cellular phe...

Full description

Bibliographic Details
Main Author: Pfäffle, Heike
Format: Others
Published: Ludwig-Maximilians-Universität München 2013
Subjects:
Online Access:http://edoc.ub.uni-muenchen.de/16240/1/Pfaeffle_Heike_N.pdf
http://nbn-resolving.de/urn:nbn:de:bvb:19-162407