Genome maintenance by Selenoprotein H in the nucleolus

<p>Selenoprotein H (SELENOH) is a nucleolar oxidoreductase with DNA binding properties whose function is not well understood. To determine the functional and physiological roles of SELENOH, a knockout of SELENOH was generated in cell lines using CRISPR/Cas9-mediated genomic deletion and in mic...

Full description

Bibliographic Details
Main Author: Zhang, Li
Other Authors: Din-Pow Ma
Format: Others
Language:en
Published: MSSTATE 2017
Subjects:
Online Access:http://sun.library.msstate.edu/ETD-db/theses/available/etd-10192017-090129/