Characterization of the relationship of ROS and Bcl-2 family members during Streptococcus pneumoniae and Staphylococcus aureus challenge

<p>Apoptosis of innate immune is an important part of proper resolution of infection and inflammation. One major protein involved in apoptosis is p53 up-regulated mediator of apoptosis (PUMA). We hypothesize apoptosis induced by the p53/PUMA pathway is initially triggered by ROS thereby preven...

Full description

Bibliographic Details
Main Author: Heath, Katie
Other Authors: Justin A. Thornton
Format: Others
Language:en
Published: MSSTATE 2015
Subjects:
Online Access:http://sun.library.msstate.edu/ETD-db/theses/available/etd-03252015-180218/