Characterization of the relationship of ROS and Bcl-2 family members during Streptococcus pneumoniae and Staphylococcus aureus challenge
<p>Apoptosis of innate immune is an important part of proper resolution of infection and inflammation. One major protein involved in apoptosis is p53 up-regulated mediator of apoptosis (PUMA). We hypothesize apoptosis induced by the p53/PUMA pathway is initially triggered by ROS thereby preven...
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Format: | Others |
Language: | en |
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MSSTATE
2015
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Online Access: | http://sun.library.msstate.edu/ETD-db/theses/available/etd-03252015-180218/ |