NMR investigations of the role of intrinsic flexibility of the tryptophan repressor
The tryptophan repressor protein regulates intracellular concentration of Tryptophan in Escherichia coli by binding to DNA operators and is activated in the presence of high L-Trp concentration by formation of an L-Trp-bound holo-repressor. A Leu to Phe mutation at position 75 generates a temperatur...
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Language: | en |
Published: |
2012
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Online Access: | http://etd.lib.montana.edu/etd/2012/goel/GoelA0512.pdf |