Structural and functional consequences of platinum anticancer drug binding to free and nucleosomal DNA

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2010. === Vita. Cataloged from PDF version of thesis. === Includes bibliographical references. === Cisplatin, carboplatin, and oxaliplatin are three FDA-approved members of the platinum anticancer drug family. These compound...

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Bibliographic Details
Main Author: Todd, Ryan Christopher, 1981-
Other Authors: Stephen J. Lippard.
Format: Others
Language:English
Published: Massachusetts Institute of Technology 2010
Subjects:
Online Access:http://hdl.handle.net/1721.1/57802