Poly(ethylene glycol)-based open-channel blockers for the acetylcholine receptor : mechanistic and structure-function studies at the single-channel level

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2009. === Vita. === Includes bibliographical references. === Ion channels are essential mediators in nervous signaling pathways. Because hyperactivation of ion channels can lead to pathological disorders such as congenital m...

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Bibliographic Details
Main Author: Lin, Wan-Chen, Ph. D. Massachusetts Institute of Technology
Other Authors: Stuart S. Licht.
Format: Others
Language:English
Published: Massachusetts Institute of Technology 2009
Subjects:
Online Access:http://hdl.handle.net/1721.1/46643