Structure-function studies of agonist binding to the muscle-type nicotinic acetylcholine receptor and the development of a trifunctional non-competitive antagonist suitable for activity-dependent profiling
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2008. === Vita. === Includes bibliographical references. === The muscle-type nicotinic acetylcholine receptor (AChR) is a ligand-gated ion channel required for fast synaptic transmission at the neuromuscular junction. It is...
Main Author: | |
---|---|
Other Authors: | |
Format: | Others |
Language: | English |
Published: |
Massachusetts Institute of Technology
2009
|
Subjects: | |
Online Access: | http://hdl.handle.net/1721.1/46035 |