Insights into the regulation of mTOR signaling and the consequences of pharmacological inhibition

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2008. === Includes bibliographical references. === Cells have evolved a highly tuned system for driving growth in response to the right cues. Permissive signals initiate a cascade of events that send nutrient transporters to t...

Full description

Bibliographic Details
Main Author: Thoreen, Carson Cornell
Other Authors: David M. Sabatini.
Format: Others
Language:English
Published: Massachusetts Institute of Technology 2009
Subjects:
Online Access:http://hdl.handle.net/1721.1/45310