Deoxyribose oxidation chemistry and endogenous DNA adducts

Thesis (Ph. D.)--Massachusetts Institute of Technology, Biological Engineering Division, 2006. === Includes bibliographical references. === Endogenous and exogenous oxidants react with cellular macromolecules to generate a variety of electrophiles that react with DNA produce cytotoxic and mutagenic...

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Bibliographic Details
Main Author: Zhou, Xinfeng
Other Authors: Peter C. Dedon.
Format: Others
Language:English
Published: Massachusetts Institute of Technology 2007
Subjects:
Online Access:http://hdl.handle.net/1721.1/37954