The germline- and tissue-specific effects of endogenous point-mutant p53
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2005. === Vita. === Includes bibliographical references. === p53 is frequently altered in human tumors through missense mutations that result in accumulation of mutant p53 protein. These mutations may confer dominant-negative...
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Format: | Others |
Language: | English |
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Massachusetts Institute of Technology
2008
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Online Access: | http://dspace.mit.edu/handle/1721.1/31186 http://hdl.handle.net/1721.1/31186 |