The germline- and tissue-specific effects of endogenous point-mutant p53

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2005. === Vita. === Includes bibliographical references. === p53 is frequently altered in human tumors through missense mutations that result in accumulation of mutant p53 protein. These mutations may confer dominant-negative...

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Bibliographic Details
Main Author: Olive, Kenneth P
Other Authors: Tyler Jacks.
Format: Others
Language:English
Published: Massachusetts Institute of Technology 2008
Subjects:
Online Access:http://dspace.mit.edu/handle/1721.1/31186
http://hdl.handle.net/1721.1/31186