Biomolecular ligand design : enhancing binding affinity and specificity utilizing electrostatic charge optimization and packing techniques
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2004. === Vita. === Includes bibliographical references (p. 257-281). === Theory and methods to design ligands with enhanced binding affinity and specificity for use as biological therapeutics were developed. These methods i...
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| Format: | Others |
| Language: | English |
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Massachusetts Institute of Technology
2005
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| Online Access: | http://hdl.handle.net/1721.1/17740 |