Subcellular basis of vitamin C protection against doxorubicin-induced changes in cardiomyocytes and Sca-1 positive cells

Understanding the molecular basis of doxorubicin (Dox)-induced oxidative stress leading to cardiomyopathy is crucial to finding cardioprotective strategies to manage this important clinical problem. Improving the antioxidant defenses of cardiac cells could be one strategy for cardioprotection. The r...

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Bibliographic Details
Main Author: Ludke, Ana
Other Authors: Singal, Pawan (Physiology)
Published: Springer/Kluwer Academic Publishers 2012
Subjects:
Online Access:http://hdl.handle.net/1993/9677