Study of polymer hydration and drug release: texture analysis and model evaluation
Hydrophilic polymers in a swellable matrix tablet hydrate quickly to form a hydrogel layer on the exterior of the dosage once in contact with water or biologic fluid. The resultant hydrogel serves as a barrier to regulate water permeation into the matrix and drug diffusion from the preparation. It i...
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2012
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| Online Access: | http://hdl.handle.net/1993/8115 |