The role of Dlc-2 in ceramide signaling to PGP synthase

The purpose of this project was to determine how Dlc-2 and Rho signaling modulate the ceramide induction of PGP synthase. This induction was studied at the transcriptional, post-transcriptional, and post-translational levels using cell culture, Real-Time RT-PCR, protein purification, phage display,...

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Bibliographic Details
Main Author: Shields, Caroline
Other Authors: Mowat, Michael (Biochemistry & Medical Genetics)
Language:en_US
Published: 2010
Subjects:
Rho
Online Access:http://hdl.handle.net/1993/4147