Scleraxis is a mechanoresponsive regulator of the cardiac myofibroblast phenotype
Cardiac fibrosis is the excess deposition of myocardial extracellular matrix components, which increases tissue stiffness and heterogeneity, causing impaired diastolic/systolic function and arrhythmias, and eventually leading to heart failure and death. There are no available treatments for cardiac...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
2015
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/1993/30354 |