Studying chemical modification and limited proteolysis of E. coli citrate synthase by mass spectrometry
Citrate synthase (CS) of 'E. coli' is strongly inhibited by the binding of NADH to an allosteric site distinct from the enzyme's active site. Previous chemical modification and mutagenesis studies have implicated a reactive cysteine, C206 as being at or near the allosteric site. This...
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| Language: | en_US |
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2007
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| Online Access: | http://hdl.handle.net/1993/2432 |