A comparative characterization of methyl-CpG binding protein 2 isoforms in the developing and adult mouse brain

A comparative characterization of methyl-CpG binding protein 2 isoforms in the developing and adult mouse brain

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Methyl-CpG binding protein 2 (MeCP2) is an epigenetic regulator in brain that binds to both methylated and hyroxymethylated DNA with similar affinities. MeCP2 has two isoforms, MeCP2E1 and MeCP2E2 with distinct N-terminus. These isoforms are generated by alternative splicing of the MECP2/Mecp2 gene....

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Bibliographic Details
Main Author:	Ezeonwuka, Chinelo Dorris
Other Authors:	Mojgan, Rastegar (Biochemistry and Medical Genetics)
Published:	2013
Subjects:	MeCP2 Expression
Online Access:	http://hdl.handle.net/1993/22028

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