A comparative characterization of methyl-CpG binding protein 2 isoforms in the developing and adult mouse brain

Methyl-CpG binding protein 2 (MeCP2) is an epigenetic regulator in brain that binds to both methylated and hyroxymethylated DNA with similar affinities. MeCP2 has two isoforms, MeCP2E1 and MeCP2E2 with distinct N-terminus. These isoforms are generated by alternative splicing of the MECP2/Mecp2 gene....

Full description

Bibliographic Details
Main Author: Ezeonwuka, Chinelo Dorris
Other Authors: Mojgan, Rastegar (Biochemistry and Medical Genetics)
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1993/22028