Structure-function analysis of a mitochondrial cell death protein, Bcl-2/E1B 19K interacting protein 3 (BNip3)
BNip3 resembles Bcl-2-related proteins, based on sequence similarity to the Bcl-2 homology 3 (BH3) domain and COON-terminal transmembrane (TM) domain. Characteristically, the 'BH3-only' class of Bcl-2 proteins heterodimerize with Bcl-2/Bcl-xL and induce cell death through their BH3 domain....
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| Language: | en_US |
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2007
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| Online Access: | http://hdl.handle.net/1993/1922 |